ComfortCaine is a topical anesthetic for oral mucosal application. ComfortCaine contains the active ingredient ethyl 4-amino benzoate 20% Benzocaine for numbing the gums. It is a flavored polyethylene glycol base sweetened with saccharin (artificial sweetener). ComfortCaine has a rapid onset (15-20 seconds) and lasts for a short period (12-15 minutes) with virtually no systemic absorption. Its smooth, even consistency lubricates as well as anesthetizes.